Free Declaration - District Court of Delaware - Delaware

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IN THE UNITED STATES DISTRICT COURT FOR THE DISTRICT OF DELAWARE PDL BIOPHARMA, INC. ) ) Plaintiff, ) ) v. ) ) ALEXION PHARMACEUTICALS, INC., ) ) Defendant. )

C. A. No. 07-156 (JJF)

DECLARATION OF KAREN JACOBS LOUDEN IN SUPPORT OF PDL'S ANSWERING BRIEF IN OPPOSITION TO DEFENDANT'S RENEWED MOTION TO BIFURCATE AND STAY TRIAL OF DAMAGES AND WILLFULNESS ISSUES 1. I am a partner at Morris, Nichols, Arsht, & Tunnell, LLP, counsel for

plaintiff PDL BioPharma, Inc. I submit this Declaration in support of PDL's Answering Brief In Opposition To Defendant's Renewed Motion To Bifurcate And Stay Trial Of Damages And Willfulness Issues. 2. Attached as Exhibit 1 is a true and correct copy of the excerpts from the

publication entitled "Understanding DNA and Gene Cloning" by K. Drlica, published by Public Health Research Institute, New York (3rd ed. 1997). 3. Attached as Exhibit 2 is a true and correct copy of the excerpts from Form

10-K filed by PDL BioPharma, Inc. with the SEC for the fiscal year ended December 31, 2007, stating that humanized antibody products with sales, in the aggregate, of billions of dollars per year are sold under license to the patents-in-suit by companies such as Genentech, Inc., MedImmune, Inc., Wyeth, and Elan Corporation, Plc. 4. Attached as Exhibit 3 is a true and correct copy of the excerpts from Form

10-K filed by Alexion Pharmaceuticals, Inc. with the SEC for the fiscal year ended December 31, 2007, describing Soliris® as a "humanized antibody" and stating that "[t]he initial indication for which [Alexion] received FDA and E.C. approval for Soliris was PNH." 5. Attached as Exhibit 4 is a true and correct copy of U.S. Patent No.

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6,355,245 B1, issued on March 12, 2002.

I declare under penalty of perjury that the foregoing is true and correct.

/s/ Karen Jacobs Louden
_____________________________________ Karen Jacobs Louden (#2881) May 23, 2008
2339495

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CERTIFICATE OF SERVICE I, the undersigned, hereby certify that on May 23, 2008, I electronically filed the foregoing with the Clerk of the Court using CM/ECF, which will send notification of such filing(s) to the following: Josy W. Ingersoll I also certify that copies were caused to be served on May 23, 2008, upon the following in the manner indicated: BY HAND Josy W. Ingersoll Andrew A. Lundgren Young, Conaway, Stargatt & Taylor, LLP The Brandywine Building 1000 West Street, 17th Flr. Wilmington, DE 19801 BY EMAIL Gerald J. Flattmann, Jr. Christine Willgoos Gregory A. Morris Kirkland & Ellis 153 East 53rd Street New York, NY 10022-4611

/s/ Karen Jacobs Louden
___________________________ Karen Jacobs Louden

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